Biological aging rate describes how fast biological damage accumulates over time, independent of chronological age.
It is a dynamic measurement, capturing the speed and direction of biological change rather than providing a static age estimate.
In the system developed by Argeron Medical, biological aging rate is measured directly using a patented LC-MS diagnostic kit, without reliance on artificial intelligence.
These concepts are often used interchangeably, but they are fundamentally different:
Two individuals of the same chronological or biological age may have very different aging rates.
Only aging rate reveals whether biological systems are:
Static age estimates provide limited clinical insight.
Biological aging rate enables:
Because it is inherently time-dependent, aging rate functions as a predictive indicator, not merely a descriptive one.
To measure aging rate reliably, the underlying biomarker must reflect irreversible, cumulative biological change.
The Argeron approach is based on protein deamidation kinetics:
These properties make protein deamidation a stable molecular substrate for rate-based measurement.
Biological aging rate in the Argeron system is measured through a single-step diagnostic process:
1. Patented Diagnostic Measurement
This measurement is performed locally by the laboratory or hospital and can be clinically interpreted on its own.
2. Optional Post-Measurement Interpretation
After measurement, results may optionally be contextualized using additional analytical tools, including reference-based decision support systems.
Artificial intelligence, when used, operates after the diagnostic result is generated and does not influence the measurement itself.
Liquid chromatography–mass spectrometry (LC-MS) is uniquely suited for aging-rate measurement because it provides:
The Argeron diagnostic kit is designed to integrate seamlessly with standard LC-MS workflows across clinical and research settings.
Epigenetic clocks estimate biological age based on DNA methylation patterns.
While useful for population-level studies, epigenetic clocks are limited in their ability to measure aging dynamics.
Key distinctions:
As a result, protein-based aging rate measurement is better suited for longitudinal clinical assessment. .
Measuring biological aging rate enables clinicians and researchers to:
It shifts aging assessment from estimation to measurement.
Biological aging rate is not about how old a system is —
it is about how quickly it is changing.